Hospital No.1, located on the grounds of the old Hessian Barracks in Frederick, becomes the most innovative hospital in a vast hospital national network that coped with all the death and destruction during the Civil War.
Frederick suffers through every day of the War. After the Battle of Antietam (1862) it cares for more wounded than the town’s population. Advances at Hospital No.1 include eliminating hospital gangrene and using plastic surgery for disfiguring wounds.
Another major Civil War hospital is at Point Lookout in St. Mary’s County, now a state park.
In 2000 the National Museum of Civil War Medicine (NMCWM) opens in downtown Frederick, the first museum devoted entirely to the story of the medical challenges associated with the four years of conflict.

Claire McCardell, fashion designer of modern women’s sportwear
Fashion designer Claire McCardell, featured on the cover of Time in 1955, is the successful creator everyday easy-to-wear clothing for women.